Autori: Charlton R, Jordan S, Pierini A, Garne E, Neville A, Hansen A, Gini R, et al.
Rivista: BJOG. Oct 2014




Abstract
OBJECTIVE
To explore the prescribing patterns of selective serotonin reuptake inhibitors (SSRIs) before, during and after pregnancy in six European population-based databases.

DESIGN
Descriptive drug utilisation study.

SETTING
Six electronic healthcare databases in Denmark, the Netherlands, Italy (Emilia Romagna/Tuscany), Wales and the rest of the UK.

POPULATION
All women with a pregnancy ending in a live or stillbirth starting and ending between 2004 and 2010.

METHODS
A common protocol was implemented across databases to identify SSRI prescriptions issued (UK) or dispensed (non-UK) in the year before, during or in the year following pregnancy.

MAIN OUTCOME MEASURES
The percentage of deliveries in which the woman received an SSRI prescription in the year before, during or in the year following pregnancy. We also compared the choice of SSRIs and changes in prescribing over the study period.

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